The medical leader of CCTR is prof. dr. Onno van Schayck (MUMC+), the technical leader is prof. dr. Hermie Hermens (UT).
Managing directors are:
Prof. Luc de Witte (MU), prof. dr. Miriam Vollenbroek (UT), prof. Roland Friele (NIVEL) and dr. Cyrille Krul (TNO) are the managing directors. They are responsible the for day-to-day coordination in and between the partner organizations, and for the development of the centre as a whole, including the education of PhD students. Together they constitute the management team.
The managing directors will be directed by the scientific leaders of CCTR and supported by their ‘home’ organizations. Within their home organization the managing directors will be responsible for the direction of the developments and the necessary decisions for the successful development of CCTR.
Three major themes with intersecting lines
The CCTR programme will have a matrix organization: three major themes with intersecting lines. These lines are:
- technical development and engineering,
- effect and process evaluation,
- integration into practice, implementation,
- safety and quality,
- ethical and societal aspects.
Separate from the content of these three themes and the intersecting lines in this matrix, specific attention will be given to valorization of the programme results.
The scientific programme will be developed and updated annually by the management team, in collaboration with all principal investigators involved in the centre, and external stakeholders, under the coordination of the managing directors.
To organize the input of external stakeholders, an advisory council with three ‘chambers’ will be installed:
- a clinical chamber consisting of clinicians and representatives of the healthcare providers who are the focus of the centre;
- a chamber with representatives of relevant patient organizations and policymakers;
- a chamber with representatives of enterprises involved in the centre.
Internal procedure for quality assurance
An internal procedure will be developed for quality assurance, and include a peer review of research proposals and scientific output. An independent committee will coordinate this procedure and will advise the managing directors and the scientific leaders.
Three criteria for each project
Each project within CCTR will have to meet the standards on each of three criteria:
- scientific quality,
- clinical/practical relevance
- valorization opportunities.
For each of these criteria an assessment protocol will be developed. Each project must be judged above the threshold on each criterion. Projects will be evaluated on a yearly basis. Appearing weaknesses will be actively dealt with and projects will be stopped if the results are expected to be insufficient.
The research programme development will be guided by clear roadmaps for each of the three main themes. These roadmaps are developed in close collaboration with all external partners and the advisory council. When these roadmaps are put into operation, specific projects will be developed and funding will be sought.
Funding will initially be sought from existing programmes on regional, national and international levels (e.g. ZonMw, NWO, Agentschap NL, disease specific funds, provinces, national government, FP7), later combined with funds from the national IMDI programme.
The allocation of available resources is the task of the management team, which will have to find a balance between directing the programme within the confines of the long-term programme and thematic roadmaps on the one hand and bottom-up initiatives of scientific staff members and external partners on the other.